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Life Science and Chemistry

February 15, 2023

Life Science and Chemistry


ATT is the largest supplier of advanced materials to the biomaterials industry with a portolio comprised of hundreds of products including biocompatible metals and alloys, advanced ceramics and oxides, organometallics, and nanomaterials.


ATT manufactures a comprehensive catalog of heterogeneous and homogeneous catalyst products for chemical synthesis, pharmaceutical manufacturing, fuel cells, hydrogen storage, and other applications utilizing catalysis reactions. Products groups include platinum group metals (PGM), organometallic compounds, nickel compounds, metal-organic frameworks (MOFs), boronic acids, alloys, carbon composites, and numerous other materials.


Salts are ionic compounds composed of cations and anions in appropriate proportions to produce electrically neutral species. Salts are named by cation species first followed by anion species. Examples of common salts include sodium chloride, sodium bisulfate, calcium chloride and potassium dichromate.


Halides

Halides are compounds in which a halogen atom (fluorine, chlorine, bromine, iodine) acts as the anionic species bound to a cationic species. Metal halides are typically used for lighting, photographic films and other applications depending on the specific compound. Fluorides are used in toothpastes, as a food additive, in optical materials, and in biological applications as a phosphatase inhibitor. Chlorides are frequently used in electrolysis and desalination. Bromides are found in veterinary medicine and diagnostics. Iodides are added to table salt as a supplement. Many metal halides serve as important precursor materials in thin film deposition and, more recently, in the formation of perovskite solar cells.


Oxyanions

Oxyanions are polyatomic anions which incorporate oxygen and can be formed by a majority of elements. Common oxyanion compounds include borates, bromates, bromides, carbonates, chlorates, chlorites, phosphates, nitrates, silicates, and sulfates. Oxyanions are named by the oxidation state of the central oxygen-bound atom. Examples of oxyanions include phosphate compounds which are found abundantly in biological systems as energy storage compounds, ATP and ADP, nitrate compounds which are used in fertilizers and as oxidizing agents, and carbonates found in biological systems to function as a pH buffer.


Products

LIFE SCIENCES

The ATT broad life sciences product portfolio of biochemicals and reagents augments our existing catalog of materials such as inorganic salts, high purity metals, organometallics, and nanomaterials to in combination support researchers & manufacturers across all fields of study and industrial production.


BIOMATERIALS

ATT supplier of advanced materials to the biomaterials industry with a portolio comprised of hundreds of products including biocompatible metals and alloys, advanced ceramics and oxides, organometallics, and nanomaterials. ATT 's in vitro biology, in vivo pharmacology, DMPK and discovery biologics services support drug discovery and early development programs. Integration of these functions, together with laboratory chemistry, CMC and safety assessment, successfully deliver preclinical candidates and IND packages.


DENTAL MATERIALS

ATT manufactures a comprehensive array of high purity and ultra high purity advanced ceramics, chemicals, metals, and alloys for dental and endodontic applications including implants and prostheses, impression materials, and others. Titanium CP (Commercially Pure) is offered in four types: CP-1 GR 4, CP-2 GR 3, CP-3 GR 2, and CP-4 GR1. We can custom manufacture materials to customer specifications for shape, size, purity, composition in all amounts including bulk quantities.


CHEMICALS & SALTS

Salts are ionic compounds composed of cations and anions in appropriate proportions to produce electrically neutral species. Halides are compounds in which a halogen atom (fluorine, chlorine, bromine, iodine) acts as the anionic species bound to a cationic species. Oxyanions are polyatomic anions which incorporate oxygen and can be formed by a majority of elements. Common oxyanion compounds include borates, bromates, bromides, carbonates, chlorates, chlorites, phosphates, nitrates, silicates, and sulfates.


CATALYSTS

ATT manufactures a comprehensive catalog of heterogeneous and homogeneous catalyst products for chemical synthesis, pharmaceutical manufacturing, fuel cells, hydrogen storage, and other applications utilizing catalysis reactions. Products groups include platinum group metals (PGM), organometallic compounds, nickel compounds, metal-organic frameworks (MOFs), boronic acids, alloys, carbon composites, and numerous other materials. American Elements can manufacture all materials in purities ranging from technical and ACS reagent grades to 99% (2N), 99.9% (3N), 99.99% (4N), 99.999% (5N), and higher, in addition to tailoring compositions to customer specifications.


ISOTOPES

Isotopes are variants of chemical elements: while all isotopes of a given element contain the same number of protons, they vary in the number of neutrons they contain. Variation in neutron number produces chemically identical atoms with different masses, which can be exploited to allow tracing of specific individual atoms through a system.


LABORATORY CHEMICALS

Under the leadership of a strong and experienced synthetic and medical chemistry management team, thousands of chemists are synthesizing compounds in a timely and cost-effective manner to meet the needs of our partners.


ORGANOMETALLICS

OXIDES

ATT specializes in manufacturing single and multi-element oxides, doped oxides, and stabilized oxides in numerous different forms. Our standard products include powders and nanopowders, pieces, pellets, shot, tablets, and sputtering targets for thin film deposition, and forms for high temperature applications such as crucibles. We can also produce many forms not listed and custom compositions by request.


WATER TREATMENT CHEMICALS

ATT produces a full line of state of the art and traditional wastewater treatment and site remediation chemicals to aid in the management of water sources including industrial wastewater, municipal water facilities, nuclear reactors, groundwater and soils contamination, and swimming pool & spa applications. Products aid in corrosion & scaling prevention, coagulation & flocculation, phosphate removal and pH adjustment.


Applications

Medical

Metabolic studies

Biochemical markers and probes are used to research the uptake of compounds by the body. For example, nutritional studies are commonly performed using isotopic labeled compounds.


Brain and kidney function

Studies of brain and kidney function are performed by tracing isotopes throughout these organs for both diagnostics and treatment applications.


Therapeutics

Precursors for therapeutic radioisotopes or radiation therapy are used for a variety of therapies. For example, neuroendocrine tumors are treated by radiotherapy using hormone bound lutetium-177 and yttrium-90.


Clinical pharmacology

Tracing drug metabolism requires the use of isotopes bound to drug in order to understand the processing of the given pharmaceutical by the body.


Research

Biology

A wide range of biochemical processes can be studied using stable isotopes. For example, a technique known as stable isotope labeling by amino acids in cell culture (SILAC) is used in proteomics research to help identify disease biomarkers.


Chemistry

The use of isotope labeling allows chemists to study the mechanisms of chemical reactions, as individual atoms can be followed through a system.


Environmental science

Isotopes are valuable for studying release and spread of pollutants in the environment.


Oceanography

The tracing of isotope movement, either within a local system such as an estuary or on a global scale, can allow study of circulation patterns.


Agriculture

Various compounds labeled with nitrogen-15 are used in the study of processes such as plant metabolism and fertilizer uptake.


Applications

Salts are found in numerous products and processes including batteries, metallurgy, renewable energy, chemical synthesis, industrial processes and biomaterials. Batteries and fuel cells typically use salts as electrolytes allowing ions to move from one electrode to another. For example salt water electrolytes are used in both fuel cells and batteries enabling the flow of current between electrodes. Another area of active research and application of salts includes using molten salts in extractive metallurgy, thermal storage, heat treatments and metal surface modification. In extractive metallurgy, one commonly used technique is to convert metals into soluble or molten salts. Steel annealing heat treatments typically make use of molten chloride salts and fluoride salts are used in the product of aluminum. In addition, metal salts are used to produce the brilliant colors of fireworks.

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